Degenerative joint disease and limb deformities cause lameness in adolescent pigs. Dyschondroplasias (osteochondroses) typified by failure of endochondral ossification are important predisposing factors for physeal and joint lesions. The youngest age when lesions develop, the primary cartilage defect, pathogenesis of lesions, and causes are not established. The purpose of the present study was to determine the age of onset and pathogensis of dyschondroplasias in pigs. Ninety-two pigs between 1 and 169 days of age were killed and …showed first 75 words of 422 total…

…showed last 75 words of 422 total…life before renal function becomes established we do not know its origin. The amniotic epithelium and blood vessels of the embryo have been suggested. The possibility of maternal origin can not be dismissed entirely. More than 200 cc. may be present in the pig when the fetus is only 30 mm. long. Certain chemical compounds, enzymes and antibodies present in the mother's body appear in the placenta and amniotic fluid but not in the fetal tissues themselves.